Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Reexamination Certificate
2006-11-07
2006-11-07
Chemyshev, Olga N. (Department: 1649)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
C435S375000, C435S325000, C435S366000, C435S448000, C435S173700, C424S093700, C424S093100
Reexamination Certificate
active
07132285
ABSTRACT:
Treatment and/or prophylaxis, in mammalian patients, of neurodegenerative and other neurological medical disorders is effected by administering to the patient effective amounts of apoptotic bodies and/or apoptotic cells, preferably those derived from the patient's own white blood cells, e.g. by extracorporeal treatment of the patient's blood cells to induce apoptosis and administration of the apoptotic bodies and/or cells so formed to the patient.
REFERENCES:
patent: 2002/0051771 (2002-05-01), Bolton, et al.
patent: 2002/0058023 (2002-05-01), Bolton, et al.
patent: 2003/0139466 (2003-07-01), Peritt et al.
patent: 2003/0157073 (2003-08-01), Peritt et al.
patent: 93/15779 (1993-08-01), None
patent: WO 98/07436 (1998-02-01), None
patent: 00/41705 (2000-07-01), None
patent: 01/66875 (2001-09-01), None
patent: WO 03/045979 (2003-06-01), None
Herrmann et al., 1998, Arthritis &Rheumatism, vol. 41, No. 7, pp. 1241-1250.
Bartholeyns et al, 1998, Res.Immunol., 149, pp. 647-649.
Bliss, T.V.P., et al., “A synaptic model of memory: long-term potentiation in the hippocampus,”Nature,361:31-39 (1993).
Bombeli, T., et al., “Apoptotic Vascular Endothlial Cells Become Procoagulant,”Blood,89:2429-2442 (1997).
Buttke and Sandstrom, et al., “Oxidative Stress As a Mediator of Apoptosis,”Immunology Today,15:7-10 (1994).
Fadok, V.A., et al., “Exposure of Phosphatidylserine on the Surface of Apoptotic Lymphocytes Triggers Specific Recognition and Removal by Macrophages,”Journal of Immunology,148:2207-2216 (1992).
Fadok, V. A., et al., “A receptor for Phosphatidylserine-specific clearance of apoptotic cells,”Nature,405:85-90 (2000).
Gavrieli, Y., et al., “Identification of Programmed Cell Death In Situ via Specific Labelling of Nuclear DNA Fragmentation,”J. of Cell Biology,119:493-501 (1992).
Griffin, W.S.T., et al., “Brain interleukin 1 and S-100 immunoreactivity are elevated in Down Syndrome and Alzheimer disease,”Proceedings of the National Academy of Sciences USA,86:7611-7615 (1989).
Guijarro, C., et al., “3-Hydrxy-3 Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle in Culture,”Circulation Research ,83:490-500 (1998).
Kerr, et al., “Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics,”British Journal of Cancer,26:239-257 (1991).
Kondo, et al., “Lymphocyte Function-Associated Antigen-1 is Required for Maximum Elicitation of Allergic Contact Dermatitis,”Br. J. Dermatol.131:354-359 (1994).
Kondo, et al., “Interleukin-10 Inhibits the Elicitation Phase of Allergic Contact Hypersensitity,”The Journal of Investigative Dermatology,103:811-814 (1994).
Loo, D. T. and Rillema, J.R., “Measurement of Cell Death,”Methods in Cell Biology,57:251-264 (1998).
Mogi, M., et al., “Interleukin (IL)-1 beta, IL-1, IL-4 , , , IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease,”Neuroscience Letters,211:13-16 (1996).
Murray, C.A., et al., “Evidence that increase hippocampal expression of the cytokine interleukin-1β is a common trigger for age and stress-induced impairments in long-term potentiation,”Journal of Neuroscience,18:2974-2981 (1998).
Salvioli, S., et al., “JC-1, but not DiOC6(3) or Rhodamine 123, is a Reliable Fluorescent Probe to Assess Δψ Changes in Intact Dells: Implications For Studies on Mitochondrial Functionality During Apoptosis,”FEBS Letters,411:77-82 (1997).
Susin, S.A., “Mitochondrial Release of Caspase-2 and -9 During the Apoptotic Process,”Journal of Experimental Medicine,189:381-394 (1994).
Suzuki, Y., “Cell Death Phagocytosis, and Neurogenesis in Mouse Olfactory Epithelium and Vomeronasal Organ After Colcicine Treatment,”Annals of the New York Academy of Sciences,855:252-254 (1998).
Teiger, E., “Apoptosis in Pressure Overload-Induced Heart Hypertrophy in the Rat,”Journal of Clinical Investigation,97:2891-2897 (1996).
Bodey, B., et al. “Apoptosis in the Mammalian Thymus During Normal Histogenesis and under Variousin Vitroandin VivoExperimental Conditions.”In Vivo.12: 123:134 (1998).
Shivji, G.M., et al. “Effects of VAS972 therapy on Ellerigc Contact Hypersensitivity.”J. Invest. Dermatol.New York, NY. 114(4): 862 (2000). (Abstract).
Marina, et al. “Apoptosis of Human Lymphocytes in the Absence or Presence of Internucleosomal DNA Cleavage”Biochemical and Biophysical Research Communications229:910-915 (1996).
Shivji, et al., The Effect of VAS972 on Allergic Contact Hypersensitivity, Journal of Cutaneous Medicine and Surgery, vol. 4, No. 3, 2000, pp. 132-138.
Bolton, “Biological Effects and Basic Science of a Novel Immune-Modulation Therapy,”Amer. J. Cardiol.95(11A):24C-29C (Jun. 6, 2005).
Maeda, et al., “Intravenous infusion of syngeneic apoptotic cells by photophoresis induces antigen-specifi regulatory T cells.”J. Immunol.174(10):5968-5976 (May 15, 2005).
Bolton Anthony E.
Mandel Arkady
Sauder Daniel
Chemyshev Olga N.
Vasogen Ireland Limited
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