Apoptosis regulating composition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31499, A61K 3150

Patent

active

056726031

ABSTRACT:
An object of the invention is to provide an apoptosis regulating composition. According to the invention, an apoptosis regulating composition is provided which comprises, as an active ingredient at least one carbostyril derivatives of general formula (1) ##STR1## and salts thereof.

REFERENCES:
patent: 4415572 (1983-11-01), Tominaga et al.
S. Sasayama et al, Acute Hemodynamic Effects of a New Inotropic Agent, OPC-8212, on Severe Congestive Heart Failure, Heart and Vessels, vol. 2, No. 1, 1986, pp. 23-28.
W. Lueprasitsakul et al, Effect of the Cardiac Inotropic Drug, OPC 8212, on Pituitary-Thyroid Function in the Rat, Endocrinology, vol. 128, No. 6, Jun. 1991, pp. 2709-2714.
R. Berkow, M.D., Editor-in-Chief, The Merck Manual of Diagnosis and Therapy, 15th Edition, 1987, Merck Sharp & Dohme Research Laboratories, Rahway, N.J., pp. 1043-1050.
F.W. Bush et al, Effects of OPC-8212, A New Positive Inotropic Agent, on the Haemopoietic System In Vitro, Experimental Hematology, vol. 19, No. 6, Jul. 1991, p. 490.

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