Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-06
1997-09-30
Travers, Russell
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31499, A61K 3150
Patent
active
056726031
ABSTRACT:
An object of the invention is to provide an apoptosis regulating composition. According to the invention, an apoptosis regulating composition is provided which comprises, as an active ingredient at least one carbostyril derivatives of general formula (1) ##STR1## and salts thereof.
REFERENCES:
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S. Sasayama et al, Acute Hemodynamic Effects of a New Inotropic Agent, OPC-8212, on Severe Congestive Heart Failure, Heart and Vessels, vol. 2, No. 1, 1986, pp. 23-28.
W. Lueprasitsakul et al, Effect of the Cardiac Inotropic Drug, OPC 8212, on Pituitary-Thyroid Function in the Rat, Endocrinology, vol. 128, No. 6, Jun. 1991, pp. 2709-2714.
R. Berkow, M.D., Editor-in-Chief, The Merck Manual of Diagnosis and Therapy, 15th Edition, 1987, Merck Sharp & Dohme Research Laboratories, Rahway, N.J., pp. 1043-1050.
F.W. Bush et al, Effects of OPC-8212, A New Positive Inotropic Agent, on the Haemopoietic System In Vitro, Experimental Hematology, vol. 19, No. 6, Jul. 1991, p. 490.
Adachi Masakazu
Aihara Koutoku
Akamatsu Seiji
Ichikawa Hiroyuki
Mori Hitomi
Otsuka Pharmaceutical Co. Ltd.
Travers Russell
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