Apoptosis inhibitor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

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Details

C514S573000, C514S912000

Reexamination Certificate

active

07129272

ABSTRACT:
Disclosed is a method for treatment of a subject having a disease or condition associated with apoptosis, which comprises administering to the subject an effective amount of a 15-keto-prostaglandin compound represented by the following formula (I):

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Feely W. F. Et al., “Normal Phase High Performance Liquid Chromatography of some Prostaglandin B-1 Derivatives” Joruanl of Liquid Chromatography, vol. 12, No. 4, 1989, pp. 515-528, XP000062725 issn: 0148-3919; p. 516, paragraph 2, p. 517.
Katzenschlager R., et al. “Synergism between PGE1-metabolites(13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation” Prostaglandins Leukot Essent Fatty Acids. Mar. 1992, 45(3)L 207-10.

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