Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-11-30
2009-02-10
Campell, Bruce (Department: 1648)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Reexamination Certificate
active
07488800
ABSTRACT:
An isolated water-soluble VP1 polypeptide of foot-and-mouth disease virus and a nucleic acid encoding the polypeptide. Also disclosed are a pharmaceutical composition containing the polypeptide or nucleic acid and related methods of inducing apoptosis and treating an apoptosis-related disorder.
REFERENCES:
Buckey et al., Nature, 397:537-539 (1999).
Jackson et al., “Arginine-Glycerine-Asparatic Acid-Specific Binding by Foot-and-Mouth Disease Viruses to the Purified Integrin αvβ3 In Vitro,” Journal of Virology, 71(11):8357-8361 (1997).
Jackson et al., J. Virology, 78:4533-4540 (2004).
Ruiz-Jarabo et al., “Antigenic Properties and Population Stability of a Foot-and-Mouth Disease Virus with an Altered Srg-Gly-Asp Receptor-Recognition Motif,” Journal of General Virology, 80:1899-1909 (1999).
Shieh et al., Vaccine, 19:4002-4010 (2001).
Tsai et al., Veterinary Microbiology, 74:207-216 (2000).
Liang Chi-Ming
Liang Shu-Mei
Peng Jei-Ming
Academia Sinica
Campell Bruce
Kinsey White Nicole
Occhiuti Rohlicek & Tsao LLP
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