Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-01-29
2008-01-29
Campell, Bruce R. (Department: 1648)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C424S184100
Reexamination Certificate
active
10863637
ABSTRACT:
An isolated water-soluble VP1 polypeptide of foot-and-mouth disease virus and a nucleic acid encoding the polypeptide. Also disclosed are a pharmaceutical composition containing the polypeptide or nucleic acid and related methods of inducing apoptosis and treating an apoptosis-related disorder.
REFERENCES:
Jackson et al. Journal of Virology. 1997; 71 (11): 8357-61.
Shieh et al. Vaccine. 2001; 19: 4002-4010.
Jackson et al. “Arginine-Glycine-Aspartic Acid-Specific Binding by Foot-and-Mouth Disease Viruses to the Purified Integrin αvβ3 In Vitro”. Journal of Virology 71(11):8357-8361, Nov. 1997.
Carmen M. Ruiz-Jarabo et al. “Antigenic properties and population stability of a foot-and-mouth disease virus with an altered Arg-Gly-Asp receptor-recognition motif.” Journal of General Virology 80:1899-1909, 1999.
Liang Chi-Ming
Liang Shu-Mei
Peng Jei-Ming
Academia Sinica
Campell Bruce R.
Kinsey Nicole
Occhiuti Rohlicek & Tsao LLP
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