Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-03-14
2006-03-14
Ungar, Susan (Department: 1642)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C530S300000, C530S350000, C536S023100, C435S007210
Reexamination Certificate
active
07011951
ABSTRACT:
A polypeptide possessing an action of causing chromatin condensation; a sense nucleic acid encoding the polypeptide; an antisense nucleic acid thereof, a probe or primer capable of specifically binding to the nucleic acid; an antibody or a fragment thereof against the polypeptide; an agent for controlling apoptosis, comprising the nucleic acid, the polypeptide, or the antibody or a fragment thereof; a screening method for a substance for controlling chromatin condensation, comprising evaluating an activity of causing chromatin condensation exhibited by the polypeptide; and a substance for controlling chromatin condensation. The present invention is useful for screening a substance controlling apoptosis, its use for controlling apoptosis and its applications to various diseases accompanying apoptosis.
REFERENCES:
patent: WO 98/54963 (1998-12-01), None
patent: WO9854963 (1998-12-01), None
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Eguchi Yutaka
Sahara Setsuko
Tsujimoto Yoshihide
Birch & Stewart Kolasch & Birch, LLP
Davis Minh-Tam
Shionogi & Co., LTD
Ungar Susan
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