Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-01-08
2008-01-08
Kaushal, Sumesh (Department: 1632)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100, C435S325000
Reexamination Certificate
active
09655109
ABSTRACT:
The invention relates to the field of apoptosis. The invention provides novel therapeutic possibilities, for example novel combinatorial therapies or novel therapeutic compounds that can work alone, sequentially to, or jointly with apoptin, especially in those cases wherein p53 is (partly) non-functional.
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Noteborn, et al. (1994) “A single chicken anemia virus protein induces apoptosis.”J Virol68, 346-351.
Noteborn, et al. (1998) “Chicken anemia virus: Induction of apoptosis by a single protein of a single-stranded DNA virus.”Seminars in Virology8, 497-504.
Paulovich, et al. (1997) “When checkpoints fail.”Cell88, 315-321.
Pietersen et al. (1999) “Specific tumor-cell killing with adenovirus vectors containing the apoptin gene.”Gene Therapy6, 882-892.
Zhuang, et al. (1995) “Apoptin, a protein derived from chicken anemia virus, induces a p53-independent apoptosis in human osteosarcoma cells.”Cancer Research55, 486-489.
Danen-Van Oorschot Astrid Adriana Anna Maria
Noteborn Mathieu Hubertus Maria
Kaushal Sumesh
Leadd B.V.
Montanari David A.
TraskBritt
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