Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2007-08-14
2007-08-14
Yaen, Christopher H. (Department: 1643)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
Reexamination Certificate
active
09733416
ABSTRACT:
The invention relates to the field of apoptosis. The invention provides novel therapeutic possibilities, for example novel combinatorial therapies or novel therapeutic compounds that can work alone, sequentially to, or jointly with Apoptin, especially in those cases wherein p53 is (partly) nonfunctional.
REFERENCES:
patent: 5981205 (1999-11-01), Hemmings et al.
patent: 6809189 (2004-10-01), Noteborn et al.
patent: 6878692 (2005-04-01), Noteborn et al.
patent: 2003/0105315 (2003-06-01), Specht et al.
patent: 0921192 (1999-06-01), None
patent: 0921192 (1999-06-01), None
patent: 0924296 (1999-06-01), None
patent: 0924296 (1999-06-01), None
patent: 1 106 691 (1999-12-01), None
patent: 1 111 045 (2000-12-01), None
patent: 1 111 045 (2000-12-01), None
patent: WO 98/39448 (1998-09-01), None
patent: WO 99/28460 (1999-06-01), None
patent: WO 9928461 (1999-06-01), None
patent: WO 01/42461 (2001-06-01), None
Crystal, R.G. (Science, vol. 270, Oct. 1995, pp. 404-410).
Tait et al. (Clin.Canc.Res., vol. 5, Jul. 1999, pp. 1708-1714).
Gura (Science, v278, 1997, pp. 1041-1042).
Reiger et al (Glossary of Genetics and Cytogenetics, Classical and Molecular, 4th Ed., Springer-Verlay, Berlin, 1976).
Zachariae et al (Science Nov. 1996;274:1201-1204).
Teodoro et al (Genes Dev. Aug. 15, 2004;18(16):1952-7).
Overbeek (Transgenic Animal Technology 1994;p. 96-98).
Wall (Theriogenology 1996; 45:57-68).
Houdebine (J. Biotech 1994; 34:269-287).
Kappell (Current Opin Biotech 1992;3:548-553).
Cameron et al (Mol. Biol 1997;7:253-265).
Niemann (Trans Res. 1997;7:73-75).
Mullins (Hypertension 1993;22:630-633.
Mullins (Nature 1990; 344:541-544.
Hammer (Cell 1990; 63:1099-1112).
Mullins (EMBO J. 1989;8:4065-4072).
Taurog (J. Immunol 1988;141:4020-4023).
Mullins (J. Clin. Invest. 1996; 98:S37-S40.
Danen-Van Oorschot, A.A.A.M. et al., (1997). Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells. Proceedings National Academy Sciences, USA: 94, 5843-5847.
Danen-Van Oorschot, A.A.A.M. et al., (1997). BAG-1 inhibits p53-induced but not Apoptin-induced apoptosis. Apoptosis: 2, 395-402.
Noteborn et al., (1994). A single chicken anemia virus protein induces apoptosis. Journal of Virology: 68, 346-351.
Noteborn et al., (1998). Chicken anemia virus: Induction of apoptosis by a single protein of a single stranded DNA virus. Seminars in Virology: 8, 497-504.
Pietersen, A. M. et al., (1999). Specific tumor-cell killing with adenovirus vectors containing the Apoptin gene. Gene Therapy: 6, 882-892.
Thompson, C. B. (1995). Apoptosis in the pathogenesis and treatment of disease. Science: 267, 1456-1462.
Zhuang, S. -M. et al., (1995). Apoptin, a protein encoded by chicken anemia virus, induces cell death in various human hematologic malignant cells in vitro. Leukemia: 9, S1, 118-120.
Zhuang, S. -M. et al., (1995). Apoptin, a protein derived from chicken anemia virus, induces a p53-independent apoptosis in human osteosarcoma cells. Cancer Research: 55, No. 3, 486-489.
T. Jenuwein et al., (1998). Cell. Mol. Life Sci.: 54, 80-93.
T. Rozovskaia et al., (2000). Oncogene: 19, 351-357.
S. Jacobson et al., (1999). Curr. Opinion in Gen. & Dev.: 9, 175-184.
Lai C -H. et al., (2000). “Identification of novel human genes evolutionarily conserved in Cernorhabditis elegans.” Genome Res., vol. 10, No. 5, pp. 703-713.
Lai C. -H., “Homo sapiensCG1-85 protein.” EMBL Sequences Accession No. AF151843, Jun. 6, 1999.
Zhuang et al., Apoptin, a Protein Derived from Chicken Anemia Virus, Induces p53-independent Apoptosis in Human Osteosarcoma Cells, Cancer Res, Feb. 1995, pp. 486-489, vol. 55, No. 3.
Pietersen et al., Specific tumor-cell killing with adenovirus vectors containing the apoptin gene, Gene Therapy, 1999, pp. 882-892, vol. 6.
Bellamy, Christopher O.C., et al., “Cell death in health and disease: the biology and regulation of apoptosis,” Seminars in Cancer Biology, vol. 6, pp. 3-16 (1995).
Danen-Van Oorschot, A.A.A.M., et al., “Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells.” Proc. Natl. Acad Sci. USA vol. 94, pp. 5843-5847 (May 1997).
Danen-van Oorschot, et al., A.A.A.M., “BAG-1 inhibits p53-induced but not apoptin-induced apoptosis,” Apoptosis, vol. 2, No. 4, pp. 395-402 (1997).
Duke, Richard C., et al, “Cell Suicide in Health and Disease,” Scientific American, pp. 80-87 (Dec. 1996).
Noteborn, M.H.M., et al., “A Single Chicken Anemia Virus Protein Induces Apoptosis,” Journal of Virology, vol. 68, No. 1, pp. 346-351 (Jan. 1994).
Noteborn, M.H.M., et al., “Characterization of Cloned Chicken Anemia Virus DNA That Contains All Elements for the Infectious Replication Cycle.” Journal of Virology, vol. 65, No. 6, pp. 3131-3139 (Jun. 1991).
Noteborn, Mathieu H.M., et al, “Chicken Anemia Virus Induction of Apoptosis by a Single Protein of a Single-Stranded DNA Virus,” Seminars in Virology, vol. 8, pp. 497-504 (1998).
Noteborn, Mathieu H.M., et al., “Simultaneous expression of recombinant baculovirus-encoded chicken anaemia virus (CAV) proteins VP1 and VP2 is required for formation of the CAV-specific neutralizing epitope,” Journal of General Virology, vol. 79, pp. 3073-3077 (1998).
Paulovich, Amanda G , et al , “When Checkpoints Fail,” Cell, vol. 88, pp. 315-321 (Feb. 7, 1997).
Steller Hermann, “Mechanisms and Genes of Cellular Suicide,” Science, vol. 267, pp. 1445-1449 (Mar. 10, 1995).
Teodoro, Jose G, et al , “Regulation of Apoptosis by Viral Gene Products,” Journal of Virology, vol. 71, No. 3, pp. 1739-1746 (Mar. 1997).
Thompson, Craig B, “Apoptosis in the Pathogenesis and Treatment of Disease,” Science, vol. 267, pp. 1456-1462 (Mar. 10, 1995).
Strausberg, Robert, “qy85c09.x1 NCI—CGAP—Bm25Homo sapienscDNA clone Image:2018800 3′, mRNA sequence,” Jan. 7, 1999, Accession No. A1360308.
Zhao S., “Use of BAC End Sequences from Library RPC1-11 for Sequence-Ready Map building,” Mar. 15, 1999, Accession No. AQ382839.
Strausberg, Robert, “wd70d04.x1 NCI—CGAP—Lu24Homo sapienscDNA clone IMAGE:2336935 3′, mRNA sequence,” Jun. 3, 1999, Accession No. A1692778.
Benet et al., pp. 3-32, in The Pharmacological Basis of Therapeutics, 8th ed., McGraw-Hill, Inc., New York, 1990.
Jain et al., Vascular and interstitial barriers to delivery of therapeutic agents in tumors, Cancer and Metastasis Reviews, 1990, pp. 253-266, vol. 9.
Jain R.K, Delivery of Molecular Medicine to Solid Tumors, 1996, Science, pp. 1079-1080, vol. 271.
Dermer, Another Anniversary for the War on Cancer, Biotechnology, 1994, pp. 320, vol. 12.
Database GenEmbl on GenCore version 4.5, Accession No. AX015052, Oct. 1999.
Strausberg R. Database EST on GenCore version 4.5, Accession No. BE746443, Sep. 2000.
Danen-Van Oorschot et al., BCL-2 Stimulated Apoptin-induced Apoptosis, pp. 245-249 in Drug Resistance in Leukemia and Lymphoma III, ed. Kaspers et al., Kluwer Academic/Plenum Publishers, New York, 1999.
Noteborn et al., Apoptin-induced apoptosis: potential for antitumor therapy. Drug Resistance Updated, 1998. pp. 99-103, vol. 1.
Noteborn et al., Apoptin induces apoptosis in transformed cells specifically: Potentials for an antitumor therapy, Biogenic Amines, 1998, pp. 73-91, vol. 15, No. 1.
Abstract XP-002140967, May 1999.
Abstract XP-002140968, May 1995.
Abstract XP-002140969, 2000.
McDonnell et al., “Implications of apoptotic cell death regulation in cancer therapy,” Cancer Biology, 1995, pp. 53-60, vol. 6.
Mullersman et al., “The PHD finger: implications for chromatin-mediated transcriptional regulation,” TIBS 20, Feb. 1995, pp. 56-59.
Jacobson et al., “Modifying chromatin and concepts of cancer,” Chromosomes and expression mechanisms, pp. 175-184.
Lu et al., “A Novel Gene (PLU-1) Containing Highly Conserved Putative DNA/Chromatin Binding Motifs Is Specifically Up-regulated in Breast Cancer,
Danen-van Oorschot Astrid Adriana A. M.
Noteborn Mathieu Hubertus M.
Rohn Jennifer Leigh
Toschi Luisella
Weiss Bertram
Leadd B.V.
TraskBritt
Yaen Christopher H.
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