Apha-conotoxin peptides

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence

Reexamination Certificate

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Details

C514S012200, C514S014800, C530S327000, C530S857000

Reexamination Certificate

active

10895372

ABSTRACT:
The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds.

REFERENCES:
patent: 4447356 (1984-05-01), Olivera et al.
patent: 5231011 (1993-07-01), Hillyard et al.
patent: 5432155 (1995-07-01), Olivera et al.
patent: 5514774 (1996-05-01), Olivera et al.
patent: 5595972 (1997-01-01), Olivera et al.
patent: 5670622 (1997-09-01), Shon et al.
patent: 5672682 (1997-09-01), Terlau et al.
patent: 5719264 (1998-02-01), Shon et al.
patent: 5739276 (1998-04-01), Shon et al.
patent: 5866682 (1999-02-01), McIntosh et al.
patent: 5889147 (1999-03-01), Cruz et al.
patent: 5969096 (1999-10-01), Shon et al.
patent: WO9511256 (1995-04-01), None
patent: WO96/40211 (1996-12-01), None
patent: WO98/22126 (1998-05-01), None
Result 8, Geneseq database search of Dec. 29, 2006, alignment of SEQ ID No. 244 with SEQ ID No. 12 of Oliveria et al., WO/95-11256 a1.
Merriam-Webster Online Dictionary definition for “derivative,” No. 4, http://m-w.com/dictionary/derivative, printed on Jan. 8, 2007.
McIntosh, J.M. et al. (1999).Ann Rev Biochem68:59-88.

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