Apertured cell carrier

Details Apertured cell carrier Apertured cell carrier

1991-07-29

1994-05-10

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

435311, 435287, 422101, C12M 132, C12M 112

Patent

active

053106741

ABSTRACT:
An apertured cell carrier has a configuration defining first and second outer surfaces and comprising an ordered array of holes therethrough, the positions on the carrier of the holes being identifiable and the holes being sized to have the ability to contain individual living cells having a generally spherical shape therewithin, one cell only per hole, in that the holes have (i) a first cross section at the first outer surface of the carrier of such dimensions that living cells can pass through the first cross section without suffering substantial damage, (ii) a second cross section at a level intermediate between said first and second outer surfaces and of such dimensions that said living cells cannot pass through the second cross section, and (iii) a height between the first outer surface and the level of the second cross section such that either such an entire living cell or substantially such an entire living cell is containable within the hole.

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