Liquid purification or separation – With means to add treating material – Chromatography
Patent
1988-10-19
1989-10-17
Therkorn, Ernest G.
Liquid purification or separation
With means to add treating material
Chromatography
2105021, 2105101, 55386, 423308, B01D 1508
Patent
active
048745111
ABSTRACT:
In an adsorbent for use in chromatography comprised of secondary particles formed by aggregation of primary particles in the form of fine crystals of hydroxyapatite, the aggregated primary particles are sintered so as to be bonded together. The adsorbent is produced by heating the secondary particles at a temperature not lower than 300.degree. C. and not higher than the decomposition temperature thereof, and has significantly improved repetitive using properties. In a column system for use in chromatography, there are provided a main column packed with the above described adsorbent and a precolumn packed with a second adsorbent comprised of conventional hydroxyapatite particles. This column has also a significantly improved repetitive using properties.
REFERENCES:
patent: 3488922 (1970-01-01), Kirkland
patent: 3509070 (1970-04-01), Lapidow
patent: 3737516 (1973-06-01), Jenner
patent: 4070283 (1978-01-01), Kirkland
patent: 4070286 (1978-01-01), Iler
patent: 4131542 (1978-12-01), Bergna
patent: 4335086 (1982-06-01), Spencer
patent: 4389385 (1983-06-01), Ramsay
patent: 4477492 (1984-10-01), Bergna
patent: 4483773 (1984-11-01), Yang
patent: 4636316 (1987-01-01), Harris
patent: 4655917 (1987-04-01), Shackelfurd
patent: 4676898 (1987-06-01), Saxena
Snyder, Introduction to Modern Liquid Chromatography John Wiley & Sons, Inc., New York, 1979, pp. 177-180 & 203-204.
Pachla, Precolumn for High Performance Liquid Chromatography, Analytical Chemistry, vol. 48, No. 1, Jan. 1976, p. 237.
Tiselius, "Protein Chromatography on Calcium Phosphate Columns," Archives of Biochemistry & Biophysics 65, pp. 132-155 (1956).
Kawasaki Tsutomu
Kobayashi Wataru
Koken Co. Ltd.
Therkorn Ernest G.
LandOfFree
Apatite chromatography column system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apatite chromatography column system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apatite chromatography column system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1742003