Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only
Patent
1975-03-21
1977-03-22
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Polymer from ethylenic monomers only
424324, 424357, A61K 4700
Patent
active
040137856
ABSTRACT:
Preparation of APAP tablet containing fumed silica by (a) forming a solution of APAP in an organic solvent, (b) suspending or dispersing in said solution powdered fumed silica, (c) drying said suspension to form a APAP-fumed silica mix, and (d) pressing a mixture containing said APAP-fumed silica mix into a tablet.
REFERENCES:
patent: 2038694 (1936-04-01), Wiggins
patent: 2951791 (1960-09-01), Stearns
patent: 3101299 (1963-08-01), Ferrand
patent: 3148124 (1964-09-01), Gaunt
patent: 3173835 (1965-03-01), Weiner et al.
patent: 3400197 (1968-09-01), Lippmann
patent: 3923969 (1975-12-01), Baukal et al.
patent: 3946110 (1976-03-01), Hill
Cabot Corp. Brochure "Cab-O-Sil Properties and Functions" 35 pages.
Kirk-Othmer Encyclopedia of Chemical Technology vol. 12 (1954) pp. 345, 358, 359, 360, entry "Silica Gel-Materials Related to Silica Gel.".
Siffert et al. Bull. Soc. Chem. Fr. 1970 (8-9):2833-2839 "Surface Organic Derivatives of Silica; Reaction of Aerosil with Various Phenols".
Merck Index 8th Ed. (1968) p. 5 entry-Acetaminophen "APAP".
Monkhouse et al. J. Pharm. Sci. 61(9):1430- 1441 Sept. 1972 "Use of Adsorbents in Enhancement of Drug Dissolution I-II".
Rosenberg Allan H.
Weintraub Leonard
Bristol-Myers Company
Holtzman Irving
Mentis George A.
Mugford David J.
Rose Shep K.
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