Aortic preferentially expressed gene and uses thereof

Details Aortic preferentially expressed gene and uses thereof Aortic preferentially expressed gene and uses thereof

1995-06-22

1998-07-28

Degen, Nancy

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 4353201, 435325, 536 231, C12P 2102, C12N 510, C12N 1585, C07H 2104

Patent

active

057861714

ABSTRACT:
An aortic-preferentially-expressed gene-1 (APEG-1) polypeptide, DNA sequences encoding and controlling the transcription of APEG-1, methods of diagnosing vascular injury, and methods of inhibiting vascular smooth muscle cell proliferation by increasing the level of APEG-1 at the site of vascular injury.

REFERENCES:
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Hsieh et al., "APEG-1, a Novel Gene Preferentially Expressed in Aortic Smooth Muscle Cells, is Down-regulated by Vascular Injury," FASEB J. 10:6, p. A1012, No. 74 (1996).
Hsieh et al., "APEG-1, A Novel Gene Preferentially Expressed In Aortic Smooth Muscle Cells, is Down-regulated by Vascular Injury," J. Biol. Chem. (Microfilms) 271(29):17354-59 (1996).
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EMBL EST, Accession no R24327, Sequence reference yg32f04.rl, 23-APR.-1995, Homo sapiens cDNA clone 33988 5' XP002014921.
EMBL EST, Accession no W55328, Sequence reference mb12e01.rl, 06-Jun.-1996, Life Tech mouse brain, Mus musculus cDNA clone 319992 5' XP002014922.

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