Antivirally active adenine derivatives

Details Antivirally active adenine derivatives Antivirally active adenine derivatives

1984-10-05

1986-08-12

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3152

Patent

active

046056580

ABSTRACT:
Certain esters of 3-(adenin-9-yl)-2-hydroxypropanoic acid are disclosed which exhibit an improved broad spectrum antiviral activity while having a low toxicity for living cells. They can be used for treatment of virus diseases in human and veterinary practice.

REFERENCES:
patent: 4230708 (1980-10-01), De Clercq et al.
Holy et al., Collection Czechoslovak Chem. Commun., vol. 47, 1982, pp. 1392-1407.
De Clercq et al., Science, 200, 563 (1978).
Sodja et al., Acta Virol., 24, 317 (1980).
Rada et al., Chemotherapy, 26, 184 (1980).
Smee et al., Antimicrob. Ag. Chemother., 21, 66 (1982).
Kara et al., EEBS Letters 107, 187 (1979).
Votruba et al., Coll. Czech. Chem. Comm., 45, 3039 (1980).
De Clercq et al., Antivirol. Res., 3, 17 (1983).
Vince et al., J. Med. Chem., 20, 612 (1977).
Holy et al., Coll. Czech. Chem. Comm., 43, 3444 (1978).
Holy et al., Coll. Czech. Chem. Comm., 49, 2144 (1984).
De Clercq et al., "Journal of Medicinal Chemistry", vol. 22, No. 5, pp. 510-513 (1979).
De Clercq et al., "Journal of Medicinal Chemistry", vol. 28, No. 3, pp. 282-287 (1982).

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