Antiviral pharmaceutical compositions containing cyclodextrins

Details Antiviral pharmaceutical compositions containing cyclodextrins Antiviral pharmaceutical compositions containing cyclodextrins

1988-06-23

1990-09-11

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 46, 536103, A61K 918, C08B 3716

Patent

active

049563513

ABSTRACT:
An antiviral composition for adminisitration to a mammal, in particular, intranasally, for the treatment of the common cold by control of common rhinoviruses. The composition is an inclusion complex of a cyclodextrin, e.g. an .alpha.-, .beta.- or .gamma.-cyclodextrin or derivatives thereof and an antiviral agent.

REFERENCES:
patent: 4289783 (1981-09-01), Mesens
patent: 4599327 (1986-07-01), Nogradi et al.
patent: 4603123 (1986-07-01), Chiesi et al.
patent: 4727064 (1988-02-01), Pitha
patent: 4834985 (1989-05-01), Elger et al.
Al-Nakib, et al., Arch. Virology, 92, 255-260 (1987).
Al-Nakib, et al., J. Antimicrobial Chemoth., 20, 887-892 (1987).
Hayden, Antimicrobial Agents and Chemoth., June 1982, pp. 892-897.
23rd Interscience Con. Antimicrobial Agents Chemotherapy, Oct. 1983, Abstract 931.

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