Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2011-08-30
2011-08-30
Zara, Jane (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S006120, C435S091100, C435S455000, C435S458000, C435S091500, C435S023000
Reexamination Certificate
active
08008270
ABSTRACT:
Random sequence oligonucleotides that have antiviral activity are described, along with their use as antiviral agents. In many cases, the oligonucleotides are greater than 40 nucleotides in length. Also described are methods for the prophylaxis or treatment of a viral infection in a human or animal, and a method for the prophylaxis treatment of cancer caused by oncoviruses in a human or animal. The methods typically involve administering to a human or animal in need of such treatment, a pharmacologically acceptable, therapeutically effective amount of at least oligonucleotide that does not act by a sequence complementary mode of action.
REFERENCES:
patent: 3687808 (1972-08-01), Merigan, Jr. et al.
patent: 4426330 (1984-01-01), Sears
patent: 4469863 (1984-09-01), Ts'o et al.
patent: 4534899 (1985-08-01), Sears
patent: 4615697 (1986-10-01), Robinson
patent: 4806463 (1989-02-01), Goodchild et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5023243 (1991-06-01), Tullis
patent: 5023252 (1991-06-01), Hseih
patent: 5130302 (1992-07-01), Spielvogel et al.
patent: 5177198 (1993-01-01), Spielvogel et al.
patent: 5213804 (1993-05-01), Martin et al.
patent: 5218103 (1993-06-01), Caruthers et al.
patent: 5223618 (1993-06-01), Cook et al.
patent: 5225212 (1993-07-01), Martin et al.
patent: 5248670 (1993-09-01), Draper et al.
patent: 5256775 (1993-10-01), Froehler
patent: 5264221 (1993-11-01), Tagawa et al.
patent: 5264423 (1993-11-01), Cohen et al.
patent: 5264562 (1993-11-01), Matteucci
patent: 5264564 (1993-11-01), Matteucci
patent: 5276019 (1994-01-01), Cohen et al.
patent: 5278302 (1994-01-01), Caruthers et al.
patent: 5356633 (1994-10-01), Woodle et al.
patent: 5366878 (1994-11-01), Pederson et al.
patent: 5378825 (1995-01-01), Cook et al.
patent: 5386023 (1995-01-01), Sanghvi et al.
patent: 5452496 (1995-09-01), Long et al.
patent: 5476925 (1995-12-01), Letsinger et al.
patent: 5489677 (1996-02-01), Sanghvi et al.
patent: 5508270 (1996-04-01), Baxter et al.
patent: 5514788 (1996-05-01), Bennett et al.
patent: 5540935 (1996-07-01), Miyazaki et al.
patent: 5543152 (1996-08-01), Webb et al.
patent: 5556948 (1996-09-01), Tagawa et al.
patent: 5563050 (1996-10-01), Peyman et al.
patent: 5580859 (1996-12-01), Felgner et al.
patent: 5591623 (1997-01-01), Bennett et al.
patent: 5591720 (1997-01-01), Anderson et al.
patent: 5591721 (1997-01-01), Agrawal et al.
patent: 5602244 (1997-02-01), Caruthers et al.
patent: 5610289 (1997-03-01), Cook et al.
patent: 5625050 (1997-04-01), Beaton et al.
patent: 5652355 (1997-07-01), Metelev et al.
patent: 5665710 (1997-09-01), Rahman et al.
patent: 5670634 (1997-09-01), Marotta et al.
patent: 5684148 (1997-11-01), Caruthers et al.
patent: 5695979 (1997-12-01), Caruthers et al.
patent: 5705188 (1998-01-01), Junichi et al.
patent: 5750666 (1998-05-01), Caruthers et al.
patent: 5770713 (1998-06-01), Imbach et al.
patent: 5837449 (1998-11-01), Monia et al.
patent: 5952490 (1999-09-01), Hanecak et al.
patent: 5998602 (1999-12-01), Torrence et al.
patent: 6013240 (2000-01-01), Behr et al.
patent: 6013639 (2000-01-01), Peyman et al.
patent: 6133246 (2000-10-01), McKay et al.
patent: 6143881 (2000-11-01), Metelev et al.
patent: 6177246 (2001-01-01), Monia et al.
patent: 6184369 (2001-02-01), Rando et al.
patent: 6316190 (2001-11-01), Rein et al.
patent: 6346614 (2002-02-01), Metelev et al.
patent: 6506559 (2003-01-01), Fire et al.
patent: 6573099 (2003-06-01), Graham
patent: 6608035 (2003-08-01), Agrawal et al.
patent: 7358068 (2008-04-01), Vaillant et al.
patent: 2003/0119019 (2003-06-01), Winnacker et al.
patent: 2003/0162225 (2003-08-01), James et al.
patent: 2003/0232435 (2003-12-01), Dobie
patent: 2005/0009743 (2005-01-01), Sundquist et al.
patent: 0 339 842 (1989-11-01), None
patent: 0 445 131 (1991-09-01), None
patent: 0 496 813 (1992-08-01), None
patent: 0 496 813 (1994-12-01), None
patent: WO 90/04384 (1990-05-01), None
patent: WO 91/05545 (1991-05-01), None
patent: WO 92/03051 (1992-03-01), None
patent: WO 93/24510 (1993-12-01), None
patent: WO 94/02499 (1994-02-01), None
patent: WO 94/17093 (1994-08-01), None
patent: WO 94/20073 (1994-09-01), None
patent: WO 94/26764 (1994-11-01), None
patent: WO 96/10391 (1996-04-01), None
patent: WO 96/40062 (1996-12-01), None
patent: WO 97/04787 (1997-02-01), None
patent: WO 97/13499 (1997-04-01), None
patent: WO 97/30731 (1997-08-01), None
patent: WO 98/39352 (1998-09-01), None
patent: WO 99/14226 (1999-03-01), None
patent: WO 99/32619 (1999-07-01), None
patent: WO 01/75164 (2001-10-01), None
patent: WO 02/068582 (2002-09-01), None
patent: WO 03/002903 (2003-01-01), None
patent: WO 03/097661 (2003-11-01), None
patent: WO 2004/002419 (2004-01-01), None
Crooke, S., Ann. Rev. Medicine, vol. 55, pp. 61-95 (2004).
Peracchi et al., Rev. Med. Virol., vol. 14, pp. 47-64 (2004).
Agrawal et al., Molecular Med. Today, vol. 6, pp. 72-81 (2000).
Chirila et al., Biomaterials, vol. 23, pp. 321-342 (2002).
Opalinska et al., Nature Rev., vol. 1, pp. 503-514 (2002).
Adjou et al., “A novel generation of heparan sulfate mimetics for the treatment of prion diseases”, 2003,J. Gen. Virol. 84:2595-2603.
Agrawal, “Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides”, 1999,Biochim. Biophys. Acta1489:53-68.
Agrawal and Kandimalla, “Antisense therapeutics: is it as simple as complementary base recognition?”, 2000,Mol. Med. Today6:72-81.
Akhtar et al., “The delivery of antisense therapeutics”, 2000,Advanced Drug Delivery Reviews44:3-21.
Allakhverdi et al., “Inhibition of Antigen-induced Eosinophilia and Airway Hyperresponsiveness by Antisense Oligonucleotides Directed against the Common β Chain of IL-3, IL-5, GM-CSF Receptors in a Rat Model of Allergic Asthma”, 2002,Am. J. Respir. Crit. Care Med. 165:1015-1021.
Andreola et al., “DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity”, 2001,Biochemistry, 40:10087-10094.
Baker et al., “2-O-(2-Methoxy)ethyl-modified Anti-intercellular Adhesion Molecule 1 (ICAM-1) Oligonucleotides Selectively Increase the ICAM-1 mRNA Level and Inhibit Formation of the ICAM-1 Translation Initiation Complex in Human Umbilical Vein Endothelial Cells”, 1997,J. Biol. Chem. 272 (18):11994-12000.
Ball et al., “Clinical Potential of Respirable Antisense Oligonucleotides (RASONs) in Asthma”, 2003,Am. J. Pharmacogenomics3 (2):97-106.
Banks et al., “Delivery across the Blood-Brain Barrier of Antisense Directed against Amyloid β: Reversal of Learning and Memory Deficits in Mice Overexpressing Amyloid Precursor Protein”, 2001,J. Pharmacol. Exp. Ther. 297 (3):1113-1121.
Bardos et al., “Structure-Activity Relationships and Mode of Action of 5-Mercapto-Substituted Oligo- and Polynucleotides as Antitemplates Inhibiting Replication of Human Immunodeficiency Virus Type 1”, 1992,Antimicrob. Agents and Chemother. 36 (1):108-114.
Barret et al., “Evaluation of Quinacrine Treatment for Prion Diseases”, 2003,J. of Virol. 77 (15):8462-8469.
Bate et al., “Squalestatin Cures Prion-infected Neurons and Protects Against Prion Neurotoxicity”, 2004,J. of Biol. Chem. 279 (15):14983-14990.
Boussif et al., “A versatile Vector for Gene and Oligonucleotide Transfer into Cells in Culture and in vivo: Polyethylenimine”, 1995,Proc. Natl. Acad. Sci. USA. 92 (16):7297-7301.
Brigger et al., “Poly(ethylene glycol)-Coated Hexadecylcyanoacrylate Nanospheres Display a Combined Effect for Brain Tumor Targeting”, 2002,J. Pharmacol. Exp. Ther. 303 (3):928-936.
Casper, “Discovery of a Novel Target for Potential Cancer Therapy”, Joint Bayer Science Forum—ACS Nov. 24thDinner Meeting. 2003, The Filterpaper, Andy Edelbrock Bayer Corporation, p. 3 (abstract).
Caughey et al., “Sulfated Polyanion Inhibition of Scrapie-Associated PrP Accumulation in Cultured Cells”, 1993,J. Virol. 67 (2):643-650.
Chen et al., “Antisense Oligonucleotides Demonstrate a D
Juteau Jean-Marc
Vaillant Andrew
Norton Rose OR LLP
Replicor Inc.
Zara Jane
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