Antiviral formulations comprising propylene glycol and an...

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Anti-infective

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S078020, C514S171000, C514S177000, C514S262100

Reexamination Certificate

active

10334487

ABSTRACT:
A topical composition comprising an antiinflammatory glucocorticoid and a nucleoside analogue antiviral agent in a pharmaceutical carrier characterized in that the carrier comprises about 15 to about 25 weight % propylene glycol and about 10 to about 25 weight percent isopropyl C12–C22alkanoic ester. The compositions have utility in the treatment or prophylaxis of herpesvirus infections and exhibit superior antiviral and therapeutic efficacy and an improved shelf life.

REFERENCES:
patent: 0 044 543 (1981-07-01), None
patent: 0 416 739 (1990-08-01), None
patent: WO 91/11187 (1991-08-01), None
patent: WO 93/00905 (1993-01-01), None
patent: WO9624355 (1996-08-01), None
patent: WO9817316 (1998-04-01), None
Block, Remington: The Science and Practice of Pharmacy, 1995, p. 1588.
Abstract “Failure of topical..” Freeman, DJ. et al.; Antimicrob Agents Chemother May 1986; 29.
Abstract “Acyclovir bioavailability..” Parry, GE. et al.; J Invest Dermatol Jun. 1992; 98 (6): 856-63.
Spruance, Spotswood L., “Herpes simplex labialis,” Clinical Management of Herpes Viruses, 1995, pp. 3-42.
Spruance, Spotswood L. et al., “High-does, short duration, early valacyclovir . . . ,” Antimicrobial Agents and Chemotherapy, Mar. 2003, p. 1072-1080.
Spruance, Spotswood L. et al., “Acyclovir cream for treatment of herpes simplex . . . ,” Antimicrobial Agents and Chemotherapy, Jul. 2002, p. 2238-2243.
Spruance, Spotswood, L. et al., “Penciclovir cream for the treatment of herpes simplex . . . ,” JAMA, May 7, 1997, vol. 277, No. 17, pp. 1374-1379.
Spruance, Spotswood, L. et al., “The natural history of recurrent herpes . . . ,” The New England Journal of Medicine, vol. 297, No. 2, pp. 69-75.
Harmenberg, Johan G. et al., “ME-609: a treatment for recurrent herpes simplex . . . ,” Antiviral Chemistry & Chemotherapy, 14(4), pp. 205-215.
Evans, T.G. et al., “Double-blind, randomized, placebo-controlled . . . ,” Antimicrobial Agents and Chemotherapy, Jun. 202, p. 1870-1874.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antiviral formulations comprising propylene glycol and an... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antiviral formulations comprising propylene glycol and an..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antiviral formulations comprising propylene glycol and an... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3770880

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.