Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-08-16
2011-08-16
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S043000
Reexamination Certificate
active
07999001
ABSTRACT:
Disclosed herein are compounds which exhibit antiviral activity against a plurality of viruses belonging to different families such as Bornaviridae, Filoviridae, Paramyxoviridae, Rhabdoviridae, Arenaviridae, Bunyaviridae, Orthomyxoviridae, and Poxviridae. Thus, methods of preventing, inhibiting, or reducing the viral activity of various viruses are provided as well as methods of treating viral infections.
REFERENCES:
Givens et al. “Detecton of Inhibition of Bovine Viral Diarrhea Virus by Aromatic Cationic Molecules” Antimicrobial Agents and Chemotherapy, Jul. 2003, pp. 2223-2230.
Anne, J. et al. (1980) “Antifungal and Antibacterial Activities of Diarylamidine Derivatives” Antimicrobial Agents & Chemotherapy 18(2):231-239.
De. Clercq et al. (1980) “Diary1 Amidine Derivatives as Oncornaviral DNA Polymerase Inhibitors” J. Med. Chem. 23:787-795.
Tidwell et al. (1978) “Diarylamidine Derivatives with One or Both of the Aryl Moieties Consisting of an Indole or Indole-like Ring, Inhibitors of Arginine-Specific Esteroproteases” J. Med. Chem. 21(7):613-623.
Declercq, E. “Diaryl Amidine Derivatives as Oncornaviral DNA Polymerase Inhibitors”, J. Med. Chem. 1980, vol. 23, pp. 787-795.
International Search Report and Written Opinion of the International Searching Authority, or the Declaration, mailed Sep. 11, 2008 received in PCT/US08/50975.
Aman Mohammad Javad
Bavari Sina
Burnett James C.
Warfield Kelly Lyn
Arwine Elizabeth
Carter Kendra D
Padmanabhan Sreeni
The United States of America as represented by the Secretary of
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