Antiviral compositions comprising a multiple branched...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

Reexamination Certificate

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C530S329000, C424S193100

Reexamination Certificate

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08080633

ABSTRACT:
Peptides representing sequences from region 45-74 of the human CD38 leukocyte surface antigen (SEQ ID NO:1) are provided which may be used to inhibit or prevent transmission or replication of the HIV virus. The peptides have from 13 to 30 amino acids and include the amino acid sequence GPGTTK (SEQ ID NO:18) for topical application to inhibit or prevent transmission of the HIV virus.

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Savarino, A., et al., 1999, Effects of the human CD38 glycoprotein on the early stages of the HIV-1 replication cycle, The FASEB J. 13:2265-2276.

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