Antiviral combination comprising nucleoside analogs

Details Antiviral combination comprising nucleoside analogs Antiviral combination comprising nucleoside analogs

1990-11-13

1992-06-16

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 45, 514 46, 514 49, 514 50, 514258, 514262, 514265, 514885, A61K 4800

Patent

active

051225174

ABSTRACT:
Antiviral and antitumor compositions are disclosed comprising a mixture of AZT, ribavirin, d4T or CS-87 with a compound of general formula: ##STR1## wherein Z is H, OH or NH.sub.2, Y is CH, and X is selected from the group consisting of H, N(R).sub.2, SR, OR or halogen, wherein R is H, lower(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically-acceptable derivatives thereof.

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H. Mitsuya et al., PNAS USA, 84, 2033 (1987).

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