Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide
Patent
1992-04-27
1993-10-26
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using a micro-organism to make a protein or polypeptide
4352521, 435825, C12P 2104, C12R 103, C07K 754, C12N 112
Patent
active
052565483
ABSTRACT:
There is provided a new antiviral antibiotic designated herein as BU-4344V which is produced by fermentation of a BU-4344V-producing strain of a new microorganism, Actinomadura parvosata subsp. kistnae ATCC No. 55076. Antibiotic BU-4344V is recovered and purified from the fermentation broth by use of extraction, chromatography, and crystallization techniques. BU-4344V has been found to have some antibacterial activity and inhibits the growth of viruses, including influenza virus type A.
REFERENCES:
patent: 4328211 (1982-05-01), Sugawara et al.
patent: 4399067 (1983-08-01), DeBono
patent: 4882419 (1989-11-01), Malabarba et al.
patent: 4946941 (1990-08-01), Kondo et al.
"ATCC Catalogue of Bacteria & Bacteriophages" 17th Ed. 1989 pp. 7-8 Actinomadura,
Naruse Nobuaki
Oka Masahisa
Tenmyo Osamu
Tomita Koji
Algieri Aldo A.
Bristol--Myers Squibb Company
Lilling Herbert J.
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