Antiviral and antitumor xanthate pharmaceutical compositions

Details Antiviral and antitumor xanthate pharmaceutical compositions Antiviral and antitumor xanthate pharmaceutical compositions

1986-08-01

1989-07-25

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514305, 514345, 514351, 514471, 514473, A61K 31265, A61K 31445

Patent

active

048514357

ABSTRACT:
The invention refers to antiviral and antitumor compositions which are useful for the control of viruses and tumors and which, in addition to a known antiviral or antitumor active xanthate, contain an adjuvant which increases its antiviral and antitumor action. The adjuvant is an ionic, preferably an anionic, compound with a lipophilic group and a hydrophilic group, preferably an alkali metal deoxycholate or a compound the lipophilic moiety of which is a straight or branched, saturated or unsaturated, aliphatic group with six to eighteen carbon atoms, and the hydrophilic group of which has one or two carboxyl, sulphate, sulphonate, or phosphate groups, or a pharmaceutically-acceptable salt thereof.

REFERENCES:
patent: 4602037 (1986-07-01), Scherm et al.
Chemical Abstract, 80:66926q (1974) [Stelzl, G. et al., Arzneim-Forsch; 1973, 23(10), 1470-3].
Chemical Abstracts, 84:69722p (1976) [Iwata, K. et al., Proc. Int. Congr. Chemother., 8th 1973, 1,945-7].
Chemical Abstracts, 87:194677z (1977) [Iwata, K. et al., Antimicrob. Agents Chemother., 1977, 12(2), 206-12].
Chemical Abstracts, 90:67131v (1979) [Sameb, S. et al., Can. J. Microbiol. 1978, 24(11), 1321-30].
Chemical Abstracts, 90:98047b (1979) [Swiss 604, 523, Polony et al., 9/15/78].
Chemical Abstracts, 103:159038k (1985) [Viegas, C. et al., Biotechnol. Lett. 1985, 7(6), 611-14].
J. Sands et al., Antimicrobial Agents and Chemotherapy, vol. 15, No. 1, pp. 134-136 (Jan. 1979).

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