Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-06-28
1997-10-28
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, A61K 3800
Patent
active
056818157
ABSTRACT:
The present invention relates to polypeptide-containing compound(s), composition(s) comprising such compound(s) along with divalent metal ions and/or a carbohydrate moiety, their antiviral and anti-hepatoma activities, and the enhancement of activity of antiviral polypeptide-containing agents by their combination with a carbohydrate and at least one divalent metal ion. Preferably, the carbohydrate is a polysaccharide of arabinose and galactose and, independently, the at least one divalent metal ion(s) include magnesium and zinc. The carbohydrate and divalent metal ion can be present in the form of a complex. The composition has been isolated and purified from the root tubers of the Chinese plant, Zei-Bai.
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Sokolov, N.N., Fitsner, A.B., Anikeicheva, N.V. Kovalenko, N.A.; Role of Divalent Cations In The Endonucleolysis of DNA Catalyzed by Restrictases; Inst. Med. Enzymol., Moscow, USSR; VOPR. Med. Khim. (1989), 35(6) (Abstract only) Coden: VMDKAM; ISSN: 0042-8809.
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Fan Sophie
Wang Xuhui
Bell Kent L.
Chen Sophie
Herron Charles J.
Tsang Cecilia J.
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