Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-01-31
1990-12-04
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514241, 514245, 514258, 514261, 514262, 514346, 514348, 514349, 544220, 544223, 544254, 544264, 544314, 544317, 546296, 546297, 546301, 549437, 549438, A61K 31505, A61K 3152, C07D23955, C07D23956, C07D23928, C07D23936, C07D47104, C07D47300, C07D47318, C07D47332, C07D47340
Patent
active
049754343
ABSTRACT:
Cyclopentenyl pyrimidine compounds have potent anti-viral, anti-tumor and differentiating activity. Of these compounds, cyclopentenyl cytosine has proved to be particularly effective in a variety of tumors, as well as having good antiviral activity and potent differentiating properties.
REFERENCES:
Ono et al.: Chemical Abstracts 106: 33435f.
Anita et al.: Nucleic Acids Res., Symposium Series 12, 25-28, 1983.
Ohno: Nucleosides & Nucleotides 4(1&2), 21-28, 1985.
Goldin: Eur. J. Cancer, 17, 124-142, 1981.
Venditti: "Pharmacological Basis of Cancer Chemotherapy", 245-270, 1975, The Williams & Wilkins Co., Baltimore.
Driscoll John S.
Glazer Robert I.
Haces Alberto
Lim Mu'Ill
Marquez Victor E.
Benson Robert
Shen Cecilia
The United States of America as represented by the Secretary of
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