Antiviral amine and amidine derivatives of glycerol and propaned

Details Antiviral amine and amidine derivatives of glycerol and propaned Antiviral amine and amidine derivatives of glycerol and propaned

1979-10-15

1981-04-14

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

564225, 564247, A61K 31155, C07C12300

Patent

active

042620210

ABSTRACT:
Novel amine and amidine derivatives of di-O-(n-higher alkyl and alkenyl)-glycerols and -propanediols, and their pharmaceutically acceptable acid addition salts, are useful for combating viral infections in mammals. Of particular interest is 1,3-di-O-(n-hexadecyl)-2-O-(3-aminopropyl)-glycerol, and its pharmaceutically acceptable acid addition salts.

REFERENCES:
patent: 3812189 (1974-05-01), English et al.
patent: 3819702 (1974-06-01), Lafon
patent: 4034010 (1977-07-01), Hamano et al.
Patai, Saul, "The Chemistry of Amidines and Imidates", (1975), pp. 264-269, Wiley, Publ.

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