Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1990-02-16
1993-05-25
Rollins, John W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
A61K 3578
Patent
active
052137988
ABSTRACT:
The use of the active ingredient present in the juice obtained from the green hull of the kukui nut for use as an antiviral pharmaceutical agent. This active ingredient is particularly useful in the topical treatment of viral infections, such as herpes simplex, genital herpes, genital warts, herpes zoster and chickenpox. The raw liquid juice, or the juice formulated in a pharmaceutically acceptable carrier, is topically administered to the surface lesion caused by the virus. Some components present of the active ingredient in the kukui nut hull juice include methyl esters of long chain fatty acids and their isomers.
REFERENCES:
"Hawaiian Herbs of Medical Value", D. M. Kaaiakamanu et al, pp. 56 and 57.
Krauss, B., Ethnobotany of Hawaii, University of Hawaii, pp. 137-141 (1974).
Hamilton, R., The Herpes Book, pp. 1-13 and 149, (1980) J. P. Tarcher, Los Angeles.
Hall, E. H., The Kukui and Its Use in Early Hawaiin Dentistry, Hawaii Dent. et al, 8+3 (1986).
Gutarnis, J., Kahuna La'au Lapa'au, Island Heritage, pp. 24-36 (1976).
Viral Diseases, The Merck Manual, pp. 158-168 (1987), Fifteenth Edition.
Locke, D., Virus Diseases, pp. 1-6 (1978), Crown Publishers, Inc., N.Y.
Langston, D. P., Living with Herpes, pp. 1-11 (1983), Doubleday and Company, N.Y.
Manikas John T.
Manning Lawrence R.
Dolezalova Hana
Rollins John W.
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