Antiviral 5-(substituted benzal) hydantoins

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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A61K 31415

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active

042646170

ABSTRACT:
Therapeutic compositions containing a compound of the formula: ##STR1## wherein: R.sub.1, R.sub.2, and R.sub.3 are each hydrogen, hydroxy, alkoxy f 1 to 4 carbon atoms, acyloxy of 1 to 4 carbon atoms, halo, or nitro, or R.sub.2 and R.sub.3 together form --OCH.sub.2 O--; or the corresponding acylated derivatives wherein there are one or more acyl groups in the hydantoin moiety and each acyl group contains from 1 to 20 carbon atoms, and the use of said compounds to control virus infections, in particular those caused by entero and foot and mouth disease viruses of the Picorna group.

REFERENCES:
Deulofeu et al., Z. Physiol. Chem. 219, pp. 233 to end (1933).

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