Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .al

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549424, A61K 3135, C07D30928

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active

056397860

ABSTRACT:
N-Acetylneuraminic and derivatives of formula (I) ##STR1## pharmaceutical formulations thereof, their use in medicine, in particular as antiviral agents and methods for their preparation are described.

REFERENCES:
Schreiner et al., "Synthesis Of Some 2,3-Didehydro-2-Deoxysialic Acids Structurally Varied At C-4 And Their Behavior Towards Sialidase From Vibrio Cholerae", Liebigs Anns. Chemie, 1991, No. 2 pp. 129-134.
Zbiral et al., "Synthesis Of the 4-acetamido-4-deoxy analogue of N-acetylneuraminic and its behaviour towards CMP-sialate synthase", Carbohydrate Research, vol. 194, 1989, pp. C15-C18.

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