Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-06-22
1983-08-23
Demers, Arthur P.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260465E, 42424852, 42424857, 424250, 424274, 424285, 424304, 424329, 424330, 424267, 542438, 542439, 542440, 564284, 564287, 564288, 564342, 564344, 564345, 549444, A61K 31445, A61K 3140
Patent
active
044003803
ABSTRACT:
Compounds of the formula ##STR1## wherein R is H, halo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, 3,4-methylenedioxy, CF.sub.3, NO.sub.2, NH.sub.2, N(C.sub.1-4 alkyl).sub.2, CN, OH, --S(C.sub.1-4 alkyl) or --SO.sub.2 (C.sub.1-4 alkyl); R.sub.1 and R.sub.2 are independently each H or C.sub.1-4 alkyl or taken together with the attached N atom are morpholino, piperidino, pyrrolidino, piperazino, or N-- C.sub.1-4 -alkyl piperazino; and, when R is halo, C.sub.1-4 alkyl or C.sub.1-4 alkoxy, x is 0-3 and, otherwise, is 0 or 1;
REFERENCES:
patent: 2993890 (1961-07-01), Shapiro et al.
patent: 4209517 (1980-06-01), Riveron
Gvozdjakova et al., Chem. Abst. 76 (1972), #99583.
Edwards Michael L.
Ritter Harry W.
Demers Arthur P.
McDonald Raymond A.
Merrell Dow Pharmaceuticals Inc.
Stein William J.
Street Gary D.
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