Antiulcer phenoxypropylamine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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260239B, 260239BF, 26032641, 26032656, 424244, 424274, 424324, 546216, 546221, 546232, 546233, 546234, 560106, 560251, 564175, 564196, 564202, 564213, 564220, 564348, A61K 31445, C07D29514

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active

042935571

ABSTRACT:
Phenoxypropylamine derivatives of the general formula ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl or ethyl group, R.sub.2 and R.sub.3, independently from each other, represent a lower alkyl group, or together form a linear alkylene group having 4 to 7 carbon atoms which may be optionally substituted by a hydroxyl or hydroxymethyl group, and R.sub.4 represents a hydrogen atom or a group of the formula --R.sub.5 --Z in which R.sub.5 represents a lower alkylene group, and Z represents a hydrogen atom or an amino, mono- or di-(lower alkyl)-amino, hydrdoxy lower alkylamino, lower alkanoylamino, hydroxyl, lower alkoxy, lower alkanoyloxy, phenoxy, halophenoxy, benzoyloxy or halobenzoyloxy group, and
the salts thereof; to a process for production thereof; and to their medicinal use, particularly to antiulcer agents comprising these phenoxypropylamine derivatives or their salts.

REFERENCES:
patent: 3856812 (1974-12-01), Dahm et al.
patent: 3996279 (1976-12-01), Schlager
patent: 4128658 (1978-12-01), Price et al.
patent: 4134983 (1979-01-01), Baldwin
patent: 4156079 (1979-05-01), Krapcho

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