Antiulcer (alkyldithio) quinoline derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514275, 544300, 544310, 544315, 544318, 544319, 544320, 544321, 544330, 544298, 544331, A61K 31505, C07D23934, C07D23952, C07D23942

Patent

active

048596795

ABSTRACT:
Quaternary 8-(alkyldithio)-1-(2-pyrimidyl)-quinolinium salts, inhibitors of the H.sup.30 /K.sup.+ ATPase enzyme, are useful in the treatment of ulcers.

REFERENCES:
patent: 4673677 (1987-06-01), LaMattina
patent: 4808591 (1989-02-01), Santini
Clissold et al., Drugs 32: 15-47 (1986).

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