Antiulcer agent and process for preparing the same

Details Antiulcer agent and process for preparing the same Antiulcer agent and process for preparing the same

1994-02-28

1997-12-16

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 60, 514 62, A61K 31715, A61K 3170

Patent

active

056985347

ABSTRACT:
An antiulcer agent effective on prevention of ulceration and acceleration of healing of ulcers and processes for preparing the same are disclosed. The antiulcer agent comprises rhamnan (a homopolysaccharide), rhamnose or a rhamnose oligomer as an active ingredient. Rhamnan is prepared by separating rhamnan sulfate from rhamnan sulfate-containing algae and desulfurating the rhamnan sulfate. Rhamnan oligomers are prepared by hydrolyzing rhamnan obtained by desulfuration of rhamnan sulfate or by hydrolyzing microbial cells of a Bifidobacterium or polysaccharides separated therefrom.

REFERENCES:
Patent Abstract of Japan, vol. 12, No. 405 (C-539) Oct. 26, 1988 & JP-A-63 145 293 (Towa Kasei Kogyo K.K.) Jun. 17, 1988.
GB-A-2 056 856 (Kureha Kagaku Kogyo) Mar. 25, 1981.
JP-A-4 018 401 Tsumura & Co) Jan. 22, 1992.
JP-A-4 005 236 (Yakult Honsha KK) Jan. 9, 1992.
Yamada, H. et al, "Purification of Anti-Ulcer Polysaccharides from the Roots of Buplerum Falcatum", Planta Medica, vol. 57, No. 6, pp. 555-559, Dec. 1991.
Sun, X.B. et al., "Purification of an Anti-Ulcer Plysaccharide from the Leaves of Panax Ginseng", Planta Medica, vol. 58, No. 5, pp. 445-448, Oct. 1992.
JP-A-63 079 893 (Towa Kasei Kogyo K.K.) Apr. 1988 *abstract*.
JP-A-62 126 193 (Towa Kasei Kogyo K.K.) Jun. 1987 *abstract*.

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