Antiulcer agent

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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A61K 3700

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active

044434340

ABSTRACT:
The octapeptide ##STR1## where the A groups are hydrogen or a dithioether bond and salts thereof inhibit gastric and pancreatic secretions and reduce gastrointestinal blood flow in treatment of peptic ulcer disease, acute pancreatitis and Zollinger-Ellison preoperational therapy.

REFERENCES:
patent: 4282143 (1981-08-01), Sarantakis
Mattes et al., Horm. Metals. Res., 7, 508-511 (1975).
Tyden et al., N. Eng. J. Med., 299, 1466-7 (1978).
Dollinger et al., Horm. Metals. Res., 8, 74-78 (1976).

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