Antiulcer [1] benzepino[3,4-b]pyridine and compositions

Details Antiulcer [1] benzepino[3,4-b]pyridine and compositions Antiulcer [1] benzepino[3,4-b]pyridine and compositions

1984-06-21

1985-10-15

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514231, 514234, 514237, 514252, 514291, 2602444, 544126, 544361, 546 80, 546 89, A61K 3144, A61K 31535, C07D491044, C07D49504

Patent

active

045474966

ABSTRACT:
A novel [1] benzepino[3,4-b]pyridine derivative having antiulcer activity is represented by the formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group, a halogenated alkyl group, an alkoxy group or a halogen atom; R.sup.2 represents ##STR2## wherein Y represents an amino group, a substituted amino group, a heterocyclic group or a substituted heterocyclic group; Z represents a hydrogen atom, an alkyl group or an acyl group; and m is an integer of 1-3, ##STR3## wherein Z' represents a hydrogen atom or an alkyl group; Y has the same meaning as defined above, and n is 0, 1 or 2; or ##STR4## wherein Z and n have the same meanings as defined above; X represents an oxygen atom or a sulfur atom. Also disclosed are pharmaceutically acceptable acid addition salts of the compound represented by the formula (I).

REFERENCES:
Ueno et al., Chemical Abstracts, vol. 83 (1975) No. 28301m.

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