Antitumoral derivatives of ET-743

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S342000

Reexamination Certificate

active

08076337

ABSTRACT:
Derivatives of Et-743 or Et-770 or Et-729 are provided. The derivatives are of the general formula Ia.:wherein the substituent groups take various permitted meanings.

REFERENCES:
patent: 5089273 (1992-02-01), Rinehart et al.
patent: 5149804 (1992-09-01), Rinehart et al.
patent: 5256663 (1993-10-01), Rinehart et al.
patent: 5478932 (1995-12-01), Rinehart et al.
patent: 5654426 (1997-08-01), Rinehart et al.
patent: 5721362 (1998-02-01), Corey et al.
patent: 5985876 (1999-11-01), Rinehart et al.
patent: 6124292 (2000-09-01), Corey
patent: 6124293 (2000-09-01), Rinehart et al.
patent: 6316214 (2001-11-01), Rinehart et al.
patent: 6348467 (2002-02-01), Corey
patent: 6544560 (2003-04-01), Bullent et al.
patent: 6569859 (2003-05-01), Corey
patent: 6686470 (2004-02-01), Danishefsky et al.
patent: 6712023 (2004-03-01), Targotay et al.
patent: 6815544 (2004-11-01), Corey
patent: 6867334 (2005-03-01), Rinehart et al.
patent: 7115743 (2006-10-01), Rinehart et al.
patent: 7202361 (2007-04-01), Flores et al.
patent: 7241892 (2007-07-01), Cuevas et al.
patent: 7247629 (2007-07-01), Manzanares et al.
patent: 7309601 (2007-12-01), Pérez Esteban et al.
patent: 7410969 (2008-08-01), Manzanares et al.
patent: 7420051 (2008-09-01), Francesh et al.
patent: 7524956 (2009-04-01), Cuevas et al.
patent: 7622458 (2009-11-01), Rybak
patent: 7723068 (2010-05-01), Iglesias et al.
patent: RE41614 (2010-08-01), Corey
patent: 7767659 (2010-08-01), Barrasa et al.
patent: 7795260 (2010-09-01), Barrasa et al.
patent: 7919493 (2011-04-01), Flores et al.
patent: 2003/0216397 (2003-11-01), Flores et al.
patent: 2004/0002602 (2004-01-01), Francesch et al.
patent: 2004/0019056 (2004-01-01), Manzanares et al.
patent: 2004/0059112 (2004-03-01), Rinehart et al.
patent: 2004/0108086 (2004-06-01), Takahashi et al.
patent: 2005/0004018 (2005-01-01), Jimeno et al.
patent: 2006/0030571 (2006-02-01), Rinehart et al.
patent: 2006/0094687 (2006-05-01), Beijnen et al.
patent: 2007/0004691 (2007-01-01), Donald et al.
patent: 2007/0082856 (2007-04-01), Gianni et al.
patent: 2007/0128201 (2007-06-01), D'Incalci et al.
patent: 2007/0275942 (2007-11-01), Cvitkovich et al.
patent: 2008/0051407 (2008-02-01), Manzanares et al.
patent: 2008/0076772 (2008-03-01), Allavena et al.
patent: 2008/0234279 (2008-09-01), Rinehart et al.
patent: 2008/0255132 (2008-10-01), Rowinsky et al.
patent: 2008/0293725 (2008-11-01), Rosell Costa et al.
patent: 2009/0076016 (2009-03-01), Calvo Salve et al.
patent: 2009/0117176 (2009-05-01), Gilles et al.
patent: 2009/0170860 (2009-07-01), Scotto et al.
patent: 2009/0247533 (2009-10-01), Rinehart et al.
patent: 2009/0324744 (2009-12-01), Takahashi et al.
patent: 2010/0009906 (2010-01-01), Ali Elsayed
patent: 0 309 477 (1991-11-01), None
patent: 59-225189 (1984-12-01), None
patent: 60-084288 (1985-05-01), None
patent: WO 87/07610 (1987-12-01), None
patent: WO 92/09607 (1992-06-01), None
patent: WO 98/12198 (1998-03-01), None
patent: WO 98/46080 (1998-10-01), None
patent: WO 99/51238 (1999-10-01), None
patent: WO 99/58125 (1999-11-01), None
patent: WO 00/18233 (2000-04-01), None
patent: WO 00/69862 (2000-11-01), None
patent: WO 01/77115 (2001-10-01), None
patent: WO 01/87894 (2001-11-01), None
patent: WO 2009/050303 (2009-04-01), None
patent: WO 2009/138509 (2009-11-01), None
patent: WO 2009/140675 (2009-11-01), None
http://www.sigmaaldrich.com/chemistry/chemistry-products.html?TablePage=16274965; last accessed Dec. 20, 2010.
U.S. Appl. No. 06/872,189, filed Jun. 9, 1986, Kenneth L. Rinehart.
U.S. Appl. No. 06/898,906, filed Aug. 21, 1986, Kenneth L. Rinehart.
U.S. Appl. No. 07/006,395, filed Jan. 23, 1987, Kenneth L. Rinehart.
U.S. Appl. No. 07/278,629, filed Dec. 1, 1988, Kenneth L. Rinehart.
U.S. Appl. No. 07/548,060, filed Jul. 5, 1990, Kenneth L. Rinehart.
U.S. Appl. No. 07/620,427, filed Nov. 30, 1990, Kenneth L. Rinehart.
U.S. Appl. No. 07/838,149, filed Feb. 18, 1992, Kenneth L. Rinehart.
U.S. Appl. No. 08/161,340, filed Dec. 2, 1993, Kenneth L. Rinehart.
U.S. Appl. No. 08/198,449, filed Feb. 18, 1994, Kenneth L. Rinehart.
U.S. Appl. No. 08/483,182, filed Jun. 7, 1995, Kenneth L. Rinehart.
U.S. Appl. No. 08/715,541, filed Sep. 18, 1996, Elias J. Corey.
U.S. Appl. No. 09/058,499, filed Apr. 10, 1998, Kenneth L. Rinehart.
U.S. Appl. No. 09/165,892, filed Sep. 30, 1998, Elias J. Corey.
U.S. Appl. No. 09/286,242, filed Apr. 5, 1999, Kenneth L. Rinehart.
U.S. Appl. No. 09/309,947, filed May 11, 1999, Kenneth L. Rinehart.
U.S. Appl. No. 09/510,315, filed Feb. 22, 2000, Elias J. Corey.
U.S. Appl. No. 09/546,877, filed Apr. 10, 2000, Kenneth L. Rinehart.
U.S. Appl. No. 09/674,796, filed Dec. 18, 2008, Bullent Kukurtcu Targotay.
U.S. Appl. No. 09/787,461, filed Mar. 2, 2001, Estaban Cvitkovich.
U.S. Appl. No. 09/949,051, filed Sep. 7, 2001, Kenneth L. Rinehart.
U.S. Appl. No. 09/971,852, filed Oct. 3, 2001, Kenneth L. Rinehart.
U.S. Appl. No. 09/979,404, filed Mar. 6, 2002, Carmen Cuevas.
U.S. Appl. No. 10/077,700, filed Feb. 14, 2002, Elias J. Corey.
U.S. Appl. No. 10/213,711, filed Aug. 7, 2002, Elias J. Corey.
U.S. Appl. No. 10/240,963, filed Mar. 19, 2003, Maria Flores.
U.S. Appl. No. 10/257,856, filed Mar. 31, 2003, Andrés Francesch.
U.S. Appl. No. 10/257,857, filed Mar. 31, 2003, Ignacio Manzanares.
U.S. Appl. No. 10/355,500, filed Jan. 31, 2003, Bullent Kukurtcu Targotay.
U.S. Appl. No. 10/406,997, filed Apr. 2, 2003, Kenneth L. Rinehart.
U.S. Appl. No. 10/416,086, filed Sep. 17, 2003, Naoto Takahashi.
U.S. Appl. No. 10/492,320, filed Aug. 18, 2004, José Jimeno.
U.S. Appl. No. 10/503,106, filed Jun. 8, 2005, Valentin Martinez Barrasa.
U.S. Appl. No. 10/524,152, filed Aug. 24, 2005, Beatriz Perez Esteban.
U.S. Appl. No. 10/540,092, filed Sep. 22, 2005, Ana Velasco Iglesias.
U.S. Appl. No. 10/558,133, filed Nov. 15, 2006, Maurizio D'Incalci.
U.S. Appl. No. 10/575,132, filed Jul. 7, 2006, Sarah Donald.
U.S. Appl. No. 10/579,130, filed Aug. 13, 2007, Eric Rowinsky.
U.S. Appl. No. 10/579,160, filed Mar. 1, 2007, Mary Ellen Rybak.
U.S. Appl. No. 10/579,251, filed Oct. 20, 2006, Luca Gianni.
U.S. Appl. No. 10/738,973, filed Dec. 17, 2003, Elias J. Corey.
U.S. Appl. No. 11/009,237, filed Dec. 10, 2004, Kenneth L. Rinehart.
U.S. Appl. No. 11/045,595, filed Jan. 26, 2005, Ignacio Manzanares.
U.S. Appl. No. 11/132,466, filed May 18, 2005, Kenneth L. Rinehart.
U.S. Appl. No. 11/249,172, filed Oct. 11, 2005, Andrés Francesch.
U.S. Appl. No. 11/261,876, filed Oct. 28, 2005, Jacob Hendrik Beijnen.
U.S. Appl. No. 11/571,589, filed Feb. 5, 2007, Rafael Rosell Costa.
U.S. Appl. No. 11/576,115, filed May 14, 2007, Paola Allavena.
U.S. Appl. No. 11/577,790, filed Sep. 24, 2007, Erard Gilles.
U.S. Appl. No. 11/645,356, filed Dec. 22, 2006, Ignacio Manzanares.
U.S. Appl. No. 11/733,606, filed Apr. 10, 2007, Maria Flores.
U.S. Appl. No. 11/769,873, filed Jun. 28, 2007, Esteban Cvitkovich.
U.S. Appl. No. 11/774,890, filed Jul. 9, 2007, Carmen Cuevas.
U.S. Appl. No. 11/929,787, filed Oct. 30, 2007, Kenneth L. Rinehart.
U.S. Appl. No. 12/091,540, filed Jun. 4, 2008, Pilar Calvo Salve.
U.S. Appl. No. 12/094,744, filed Nov. 17, 2008, Kathleen Scotto.
U.S. Appl. No. 12/273,919, filed Nov. 19, 2008, Valentin Martinez Barrasa.
U.S. Appl. No. 12/299,960, filed Mar. 23, 2009, Yusri Ali Elsayed.
U.S. Appl. No. 12/337,756, filed Dec. 18, 2008, Elias J. Corey.
U.S. Appl. No. 12/482,753, filed Jun. 11, 2009, Kenneth L. Rinehart.
U.S. Appl. No. 12/552,347, filed Sep. 2, 2009, Naoto Takahashi.
Suggitt et al., “50 Years of Preclinical Anticancer Drug Screening: Empirical to Target-Driven Approaches,” Feb. 1, 2005, pp. 971-981, vol. 11, Clinical Cancer Research.
Cecil Textbook of Medicine, 2000, 21stEdition, pp. 1060-1074, Chapter 198, W.B. Saunders Company.
Arai, T. et al., “The Structure of a Novel Antitumor Antibiotic, Saframycin A”, Experientia, vol. 36, pp. 1025-1027 (1980).
Arai, Tadashi et al., “Increased Production of Saframycin A and Isolation of Saframycin S”, The Journal of Antibiotics, vol. XXXIII, No. 9, pp. 951-960 (1980).
Arai, Tadashi et al., “Isoquinolineinones

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