Antitumoral compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514297, 546 81, 546103, A61K 3144, C07D47106

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active

056059051

ABSTRACT:
Azaanthracene-triones of the formula: ##STR1## (in which: R.sup.1, R.sup.2, R.sup.4 and R.sup.5 are the same or are different and each is a hydrogen atom or a lower alkyl group;

REFERENCES:
Gesto et al. "Synthesis and biological activity of new 1,8-diaza-2,9,10-anthacenetrione derivatives" J. Phar. Sci. v.81 (8) 815-816 (1992).
Lee et al. "Total synthesis of 4-acetyloxymethyl-1,6,9-trimethyl-1,9-diazaanthrac ene-2,5,8,10-tetraone" Tetrahedron Lett. v.31(31)4405-4408 (1990).
Goulart et al. "Azaflurorenones and azaanthrazuinone from Guatteria dielsiana" CA 105:168866x (1986).
Gesto et al. "Synthesis of diaza-anthraquinones by hetero diels-alder cycloaddition reaction" Tetrahedron v.45 4477-4484 (1989).

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