Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-08-13
2008-07-08
Aulakh, Charanjit S. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S047000, C546S051000
Reexamination Certificate
active
07396837
ABSTRACT:
New lamellarins are provided of the general formula III or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof
REFERENCES:
patent: 5852033 (1998-12-01), Fernandez Puentes et al.
patent: 6469171 (2002-10-01), Banwell et al.
patent: 97/01336 (1997-01-01), None
patent: 98/50365 (1998-11-01), None
patent: 99/67250 (1999-12-01), None
Andersen et al., “Metabolites of the Marne Prosobranch Mollusc Lamellaria SP”,J. of Amer. Chem. Soc., vol. 107, pp. 5492-5495, 1985.
Banwell et al., “Assessment of Double-Barrelled Heck Cyclizations as a Means for Constructions of the 14-phenyl-8, 9-dihydro-6h-[1]benzopyrano[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one Core Associated with Certain Members of the Lamellarin Class of Marine Natural Product”,Aust. J. of Chem., vol. 52, pp. 755-765, 1998.
Banwell et al., “Convergent Total Synthesis of Lamellarin K”,Chem. Comm., vol. 23, pp. 2259-2260, 1997.
Cantrell et al., “A New Staurosporine Analog from the Prosobranch Mollusk Coriocella Nigra”,Natural Prod. Ltrs., vol. 14:1, pp. 39-46, 1999.
Carroll et al., “Studies of Australian Ascidians I Six New Lamellarin-Class Alkaloids from a Colonial Ascidian, Didemnum SP”,Aust. J. of Chem., vol. 46, pp. 489-501, 1993.
Cironi et al., “Solid-Phase Total Synthesis of the Pentacyclic System Lamellarins U and L”,Organic Ltrs., vol. 5:16, pp. 2959-2962, 2003.
Davis et al., “New Lamellarin Alkaloids from the Australian Acidian, Didemnum Chartaceum”,J.of Nat. Prod, vol. 62, pp. 419-424, 1999.
Diaz et al., “Syntheses of Lamellarins I and K by [3+2] Cycloaddition of a Nitrone to an Alkyne”,Synlett, vol. 7, pp. 1164-1166, 2001.
Ham et al., “A Novel Cytotoxic Alkaloid of Lamellarin Class From a Marine Ascidian Didemnum sp.”,Bull. Korean Chem. Soc., vol. 23:1, pp. 163-166, 2002.
Heim et al., “Biomimetic Synthesis of Lamellarin G Trimethyl Ether”,Angewandte Chemie Int'l Ed., vol. 36, pp. 155-156, 1997.
Ishibashi et al., “Synthesis and Structure-Activity Relationship Study of Lamellarin Derivatives”,J. of Nat. Prod., vol. 65, pp. 500-504, 2002.
Ishibashi et al., “Total Synthesis of Lamellarin D and H. The first Synthesis of Lamellarin-Class Marine Alkaloids”,Tetrahedron, vol. 53:17, pp. 5951-5962, 1997.
Iwao et al., “Short and Flexible Route to 3,4-diarylpyrrole Marine Alkaloids: Syntheses of Permethyl Storniamide A, Ningalin B and Lamellarin G Trimethyl Ether”,Tetrahedron Ltrs., vol. 44, pp. 4443-4446, 2003.
Lindquist et al., New Alkaloids of the Lamellarian Class from the Marine Ascidian Didemnum Chartaceum,J. Org. Chem., vol. 53:19, pp. 4570-4574, 1988.
Ploypradith et al., “Further developments in the Synthesis of Lamellarin Alkaloids via Direct Metal-Halogen Exchange”,Tetrahedron Ltrs., vol. 44, pp. 1363-1366, 2003.
Quesada et al., “Polyaromatic Alkaloids From Marine Invertebrates as Cytotoxic Comounds and Inhibitors of Multidrug Resistance caused by P-Glycoprotein”British J. of Cancer, vol. 74, pp. 677-682, 1996.
Reddy et al., “Lamellarin Alpha 20-Sulfate, an inhibitor of HIV- Integrase Active Against HIV-1 Virus in Cell Culture”,J. of Med. Chem., vol. 42, pp. 1901-1907, 1999.
Reddy et al., “New Lamellarin Alkaloids from an Unidentified Ascidian from the Arabian Sea”,Tetrahedron, vol. 53:19, pp. 3457-3466, 1997.
Ridley et al., “Total Synthesis and Evaluation of Lamellarin Alpha 20-Sulfate Analogues”,Bioorganic&Medicinal Chem., vol. 10, pp. 3285-3290, 2002.
Ruchirawat et al., “An Efficient Synthesis of Lamellarin Alkaloids;Synthesis of Lamellarin G Trimethyl Ether”,Tetrahedron Letters, vol. 42, pp. 1205-1208, 2001.
Urban et al., “Lamellarins O and P: New Aromatic Metabolites from the Australian Marine Sponge Dendrilla Cactos”,Aust. J. Chem., vol. 14:10, pp. 1919-1924, 1994.
Urban et al., “Lamellarin-S: A New Aromatic Metabolite From an Australian Tunicate, Didemnum SP”,Aust. J. Chem., vol. 49, pp. 711-713, 1996.
Bailly Christian
Cuevas Marchante Carmen
Francesch Andres
Jiménez Guerrero José Antonio
Mateo Urbano Maria Cristina
Aulakh Charanjit S.
King & Spalding LLP
Pharma Mar, S.A.U.
Sonnenfeld Kenneth H.
Willis Michael A.
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