Antitumor treatment method

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514301, 514367, 424422, A61K 3147

Patent

active

054911516

ABSTRACT:
This invention relates to an antitumor agent containing as the effective ingredient a cyanine dye, shown by the general formula: ##STR1## where X.sup.- is a physiologically-acceptable anion; Z.sup.+, a group of the formula ##STR2## R, an alkyl group having a carbon chain length of 1-5; and R', either hydrogen atom or an alkoxy group. Oral and parenteral administration of the antitumor agent remarkably activates macrophages in vivo and enhances their functions to allow them to inhibit the growth and metastasis of tumors, as well as to accelerate their natural death through cicatrization.

REFERENCES:
patent: 4959301 (1990-09-01), Weaver
patent: 5091385 (1992-02-01), Gulliya
Minani Chem Pharm Bull 30, p. 3106 (1982).

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