Antitumor substance BE-13793C

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548416, A61K 3140, C07D48722

Patent

active

051068648

ABSTRACT:
A novel antitumor substance BE-13793C or a pharmaceutically acceptable salt thereof, which is represented by the following formula: ##STR1## an anticancer agent comprising the novel substance or a pharmaceutically acceptable salt thereof, a method of producing the novel substance and a microorganism capable of producing the novel substance are disclosed.

REFERENCES:
T. Kaneko et al., "Two Synthetic Approaches to Rebeccamycin", Tetrahedron Letters, vol. 26, No. 34, pp. 4015-4018, (1985).
J. Bergman et al., "Synthesis of Indolo[2,3-a]pyrrolo[3,4-c]carbazoles by Double Fischer Indolizations", J. Org. Chem., vol. 54, pp. 824-828, (1989).
W. Steglich et al., "Indole Pigments from the Fruiting Bodies of the Slime Mold Arcyria Denudata", Angew. Chem. Int. Ed. Engl., vol. 19, No. 6, pp. 459-460, (1980).
Steglich Wolfgang et al., CA:93:66027r (1980) or Angew Chem. 92(6) 463-464 (1980).

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