Antitumor protein hybrid and process for the preparation thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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C07K 1514

Patent

active

046380493

ABSTRACT:
Antitumor protein hybrid, composed of a moiety which is substantially the fragment Fab of an antitumor immunoglobulin and a moiety which is substantially the fragment A of a diphtheria toxin, which is expressed by the following formula (I):

REFERENCES:
patent: 4160018 (1979-07-01), Bjorklund
patent: 4160019 (1979-07-01), Bjorklund
patent: 4174385 (1979-11-01), Reid
patent: 4201770 (1980-05-01), Stevens

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