Antitumor protein gene of streptococcus pyogenes Su, plasmids co

Details Antitumor protein gene of streptococcus pyogenes Su, plasmids co Antitumor protein gene of streptococcus pyogenes Su, plasmids co

1986-12-24

1990-05-29

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4352534, 435320, 4352523, 935 21, 935 55, 935 41, 935 72, 530350, 530820, 536 27, C12P 100, C12N 500, C12N 122, C12N 120

Patent

active

049295470

ABSTRACT:
Amino acid sequence of N-terminal region of streptococcal acid glycoprotein (SAGP), and antitumor glycoprotein produced by Streptococcus pyogenes Su, was determined, and DNA probes which are complementary to SAGP gene were synthesized.
Chromosomal DNA fragment of S.pyogenes Su, which hybridized with those probes was cloned into E.coli, and a restriction map of plasmid DNA harboring SAGP gene was revealed and upon it, DNA sequence or amino acid sequence of SAGP gene was determined.

REFERENCES:
Yoshida et al, "Jpn. J. Cancer Res. (Gann)", 76, pp. 213-223, Mar. 1985.
Masui et al, "Biotechnology", pp. 81-85, Jan. 1984.
De Boer et al, "Proc. Natl. Acad. Sci. U.S.A.", vol. 80, pp. 21-25, Jan. 1983.

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