Antitumor glycosides, process for their preparation including in

Details Antitumor glycosides, process for their preparation including in Antitumor glycosides, process for their preparation including in

1977-12-14

1980-01-15

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 4, 536 17A, A61K 3170

Patent

active

041839196

ABSTRACT:
Disclosed is a new class of antitumor glycoside antibiotics of the formula (IA): ##STR1## wherein R is hydrogen or hydroxy; and X is ##STR2## These compounds are prepared, using novel intermediates, by condensing the appropriate aglycone and amino-deoxy sugar to form the .alpha.-glycosidic linkage.

REFERENCES:
patent: 3976667 (1976-08-01), Kelly
patent: 4067969 (1978-01-01), Penco et al.
Di Marco et al., Journ. Med. Chem., vol. 17, No. 3, pp. 335-337, (1974).

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