Antitumor compositions and methods of treatment

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514593, A61K 3118

Patent

active

052349551

ABSTRACT:
This invention provides certain N-phenyl-N'-substitutedphenylsulfonylureas compounds, formulations, and a method for treating susceptible neoplasms in mammals using the sulfonylurea compounds.

REFERENCES:
patent: 3083207 (1963-03-01), Hoehn et al.
patent: 3097242 (1963-07-01), Hoehn et al.
patent: 3102115 (1963-08-01), Breuer et al.
patent: 3102121 (1963-08-01), Breuer et al.
patent: 3736122 (1973-05-01), Tung et al.
patent: 3849110 (1974-11-01), Soper et al.
patent: 4845128 (1989-07-01), Harper et al.
07/554,226, Howbert, et al., filed Jul. 17, 1990.
07/554,218, Crowell et al., filed Jul. 17, 1990.
07/351,755, Harper et al., filed May 15, 1989.
07/581,840, Harper, et al., filed Sep. 13, 1990.
07/805,417, Ehlhardt, et al., filed Dec. 10, 1991.
W. J. Ehlhardt, Drug Metabolism and Disposition, 19:370 (1991).
J. J. Howbert, et al., Synthetic Communications, 20:3193 (1990).
W. J. Ehlhardt, Drug Metabolism and Disposition, 19:366 (1991).
J. J. Howbert, et al., Journal of Medicinal Chemistry, 33:2393 (1990).
G. B. Grindey et al., Proceedings of the American Association of Cancer Research, 27:277 (Abstract 1099) (1986).
C. W. Taylor, et al., Journal of Clinical Oncology, 7:1733 (1989).
J. D. Hainsworth, et al., Cancer Research, 49:5217 (1989).
R. Levine, Diabetes Care, 7 (Suppl. 1):3-7 (1984).
G. F. Holland, et al., Journal of Medicinal and Pharmaceutical Chemistry, 3:99 (1961).
P. J. Houghton, et al., Cancer Chemotherapy and Pharmacology, 25:84 (1989).
P. J. Houghton, et al., Cancer Research, 50:318 (1990).
P. J. Houghton, et al., Cancer Research, 50:664 (1990).
P. J. Houghton, et al., Biochemical Pharmacology, 39:1187 (1990).
P. H. Dhahir, et al., In Proceedings of the 36th ASMS Conference on Mass Spectroscopy and Allied Topics, pp. 972-973 (1988).
G. F. Holland, Journal of Organic Chemistry, 26:1662 (1961).
Chemical Abstracts, 52:17180; citing Haack, et al., East German Patent 9688, Apr. 21, 1955.
F. Kurzer, Chemical Reviews, 50:1 (1952).
G. B. Grindey, et al., In Proceedings of the American Association for Cancer Research, 28:309 (Abstract 1224) (1987).
H. Breuer, et al., Chimie Therapeutique, Nov./Dec. 1973:659.
L. J. Lerner, et al., Metabolism, 14:578 (1965).
G. Jahnchen, et al., Zeitschrift Chem., 39:305 (1969).
M. Thompson, Journal of Organic Chemistry, 49:1700 (1984).
G. Foley, et al., Cancer, 18:522 (1965).
C. Goralski, et al., Journal of Chemical and Engineering Data, 21:237 (1976).
Howbert et al, J. of Medicinal Chemistry, 1990, vol. 33, No. 9, pp. 2393-2407.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antitumor compositions and methods of treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antitumor compositions and methods of treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumor compositions and methods of treatment will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1725560

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.