Antitumor antisense sequences directed against R1 and R2...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C435S006120, C435S091100, C435S091310, C435S375000, C435S455000, C435S458000, C514S001000, C536S023100, C536S024500

Reexamination Certificate

active

07405205

ABSTRACT:
Compounds and methods for modulating cell proliferation, preferably inhibiting the proliferation of tumor cells are described. Compounds that may be used to modulate cell proliferation include antisense oligonucleotides complementary to regions of the mammalian ribonucleotide reductase genes.

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