Antitumor antibiotics produced by new streptomyces

Details Antitumor antibiotics produced by new streptomyces Antitumor antibiotics produced by new streptomyces

1982-07-26

1984-08-07

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435253, 435886, C12P 1718, C12N 120, C12R 1465

Patent

active

044644671

ABSTRACT:
A novel antitumor antibiotic designated herein as BBM-2040 is produced by fermentation of Streptomyces sp. strain J576-99 (ATCC 39143). BBM-2040, which may be recovered from the fermentation broth in either a desmethanol (BBM-2040B) or methanol-adduct (BBM-2040A) form, inhibits gram-positive and acid-fast bacteria and inhibits the growth of tumors such as P388 leukemia in mice.

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