Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2

Details Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2 Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2

1977-03-24

1979-03-13

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 4, 536 17, 536 28, 536 29, A61K 3171, C07H 1708

Patent

active

041443292

ABSTRACT:
New antitumor agents designated MA 144-M.sub.1 and MA 144-M.sub.2, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria, e.g. Staphyococcus aureaus, Bacillus subtilis and Sarcina lutea, and inhibit the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180 are produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A.

REFERENCES:
patent: 3988315 (1976-10-01), Umezawa et al.
Oki et al., "The Journal of Antibiotics," vol. 28, 1975, pp. 830-834.

Affiliated with

Also associated with

Rating

Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2371695