Antitumor antibiotics BBM-2040A and BBM-2040B

Details Antitumor antibiotics BBM-2040A and BBM-2040B Antitumor antibiotics BBM-2040A and BBM-2040B

1984-05-10

1985-04-02

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

435119, 435886, C07D48704, C12P 1718, C12N 120, C12R 1465

Patent

active

045086478

ABSTRACT:
A novel antitumor antibiotic designated herein as BBM-2040 is produced by fermentation of Streptomyces sp. strain J576-99 (ATCC 39143). BBM-2040, which may be recovered from the fermentation broth in either a desmethanol (BBM-2040B) or methanol-adduct (BBM-2040A) form, inhibits gram positive and acid-fast bacteria and inhibits the growth of tumors such as P388 leukemia in mice.

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