Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure
Patent
1975-03-03
1976-11-16
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
195 80R, A61K 3574
Patent
active
039925242
ABSTRACT:
A new antitumor agent named macracidmycin, which is a macromolecular peptide and inhibits the growth of various tumor cells and experimental animal tumors such as Ehrlich ascites carcinoma and Sarcoma 180 is produced by the fermentation of a microorganism belonging to the genus Streptomyces which has been designated Streptomyces atrofaciens (M590-G2 and A.T.C.C. 31104); it is recovered from the broth by conventional methods for recovering antibiotics.
REFERENCES:
suhava et al., J. Antibiotics, Ser. A16, 1963, pp. 107-108.
Murase et al., J. Antibiotics, Ser. A14, 1961, pp. 113-118.
Nakamura et al., J. Antibiotics, Ser. A20, 1967, pp. 210-216.
Ishida et al., J. Antibiotics, 22, 1969, pp. 218- 227.
Hamada Masa
Ishizuka Masaaki
Oki Toshikazu
Takamatsu Akira
Takeuchi Tomio
Goldberg Jerome D.
Taylor, Jr. Herbert W.
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
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