Antitumor antibiotic BU-3285T compounds

Details Antitumor antibiotic BU-3285T compounds Antitumor antibiotic BU-3285T compounds

1989-11-03

1990-08-28

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30932

Patent

active

049527096

ABSTRACT:
The present invention relates to the antitumor antibiotic compound BU-3285T and its preparation. The compound is obtained by culturing a new strain of Chainia rosea and demonstrates both antitumor and antifungal activity. It also relates to the desulfated derivative of BU-3285T which is obtained by treatment of BU-3285T with sulfatase enzyme. BU-3285T desulfate possesses antitumor activity.

REFERENCES:
patent: 4495286 (1985-01-01), Tunc et al.
patent: 4578383 (1986-03-01), Stampwala et al.
patent: 4680416 (1987-07-01), Hokanson et al.
The Merck Index, Windholz et al., 10th Edition, 1983, p. 2215, Entry No. 2216.

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