Antitumor antibiotic BU-3285T

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3135

Patent

active

050895222

ABSTRACT:
The present invention relates to the antitumor antibiotic compound BU-3285T and its preparation. The compound is obtained by culturing a new strain of Chainia rosea and demonstrates both antitumor and antifungal activity. It also relates to the desulfated derivative of BU-3285T which is obtained by treatment of BU-3285T with sulfatase enzyme. BU-3285T desulfate possesses antitumor activity.

REFERENCES:
patent: 4495286 (1985-01-01), Tunc et al.
patent: 4578383 (1986-03-01), Stampwala et al.
patent: 4680416 (1987-07-01), Hokawson et al.

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